Two major shopping centres and two prominent department stores can be found on this busy street. Jervis Street Shopping centre is at the lower end of Henry Street. It is a very comprehensive shopping centre including many of the British Chains such as Boots, Debenhams and Argos.

The Ilac Shopping Centre has many interesting and lower budget shops. One entrance leads out to Moore Street's famous market and there's also a public library inside the centre.

Arnotts also stocks many fashionista's favourite brands, Miss Sixty, Mango, Tommy Hilfigger and Pepe to name but a few. It is now the oldest department store in Dublin and stocks almost everything. There is an excellent worldwide gift store in the basement called S F Cody, a large section of collectibles, homeware, Irish Crystal and Irish Glass. Arnotts also has an impressive footwear and accessories collection.

The recently redeveloped Roches Stores has also enhanced Henry Street's reputation as one of Dublin's main shopping districts. Roches Stores has exclusively introduced over 20 of the top international brands to Ireland for the first time. One of these widely acclaimed international brands, Zara is a major part of the new look Roches Stores. It is the first to open in the Republic of Ireland and is 20,000 sq ft in stature. There are five floors to the revamped Roches Stores stocking everything from Home and Giftware, Fashionwear, Accessories and Cosmetics. Roches also provide customer service desks, ATM's, the Atrium Restaurant which seats 250 people, a juice bar and a café.

There are lots of small and independent shops on Henry Street. The Body Shop, Korky's, The Levi's Store, Envy, and budget shops such as Japan and No Name can all be found on this colourful street.

Henry Street is undoubtedly one of Dublin's best shopping districts, catering for all shoppers tastes.